酒石酸噻吩嘧啶

NMR下載 COA and HPLC MSDS下載
names：
Pyrantel tartrate
CAS號：
33401-94-4
MDL Number：
MF(分子式)： C15H20N2O6S MW(分子量)： 356.39
EINECS:251-501-8 Reaxys Number:33401-94-4
Pubchem ID:5145916 Brand:BIOFOUNT

酒石酸噻吩嘧啶(Pyrantel tartrate,33401-94-4):牲畜的廣譜驅蟲藥。

貨品編碼	規格	純度	價格 (￥)	現價(￥)	特價(￥)	庫存描述	數量	總計 (￥)
YZM000792-500mg	500mg	99.58%	￥ 911.00	￥ 911.00		2-3天	- +	￥ 0.00
YZM000792-100mg	100mg	99.58%	￥ 341.25	￥ 341.25		2-3天	- +	￥ 0.00

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中文別名	酒石酸噻吩嘧啶(Pyrantel tartrate,33401-94-4)
英文別名	Pyrantel tartrate(酒石酸噻吩嘧啶,33401-94-4)
CAS號	33401-94-4
Inchi	InChI=1S/C11H14N2S.C4H6O6/c1-13-8-3-7-12-11(13)6-5-10-4-2-9-14-10;5-1(3(7)8)2(6)4(9)10/h2,4-6,9H,3,7-8H2,1H3;1-2,5-6H,(H,7,8)(H,9,10)/b6-5+;/t;1-,2-/m.1/s1
InchiKey	VWRCYAZJKNPEQR-NIEARKAZSA-N
分子式 Formula	C15H20N2O6S
分子量 Molecular Weight	356.39
溶解度Solubility	生物體外In Vitro:DMSO溶解度≥ 34 mg/mL(95.40 mM)*"≥" means soluble可溶, but saturation unknown溶解度未知.
性狀	固體粉末,Power
儲藏條件 Storage conditions	-20°C 3 years年 4°C 2 years年 / In solvent溶液中:-80°C 6 months月 -20°C 1 month月

酒石酸噻吩嘧啶(Pyrantel tartrate,33401-94-4)毒性

生物	測試類型	路線	報告劑量（標準化劑量）	影響	參考
cattle	LD	unreported	> 200mg/kg (200mg/kg)		Australian Veterinary Journal. Vol. 46, Pg. 297, 1970.
mouse	LD50	intravenous	2220ug/kg (2.22mg/kg)		Oyo Yakuri. Pharmacometrics. Vol. 5, Pg. 305, 1971.
mouse	LD50	oral	123mg/kg (123mg/kg)		Oyo Yakuri. Pharmacometrics. Vol. 5, Pg. 305, 1971.
mouse	LD50	subcutaneous	> 25mg/kg (25mg/kg)		Oyo Yakuri. Pharmacometrics. Vol. 5, Pg. 305, 1971.
rat	LD50	oral	170mg/kg (170mg/kg)		Australian Veterinary Journal. Vol. 46, Pg. 297, 1970.

酒石酸噻吩嘧啶(Pyrantel tartrate,33401-94-4)實驗注意事項：
1.實驗前需戴好防護眼鏡，穿戴防護服和口罩，佩戴手套，避免與皮膚接觸。
2.實驗過程中如遇到有毒或者刺激性物質及有害物質產生，必要時實驗操作需要手套箱內完成以免對實驗人員造成傷害
3.實驗后產生的廢棄物需分類存儲，并交于專業生物廢氣物處理公司處理，以免造成環境污染Experimental considerations:
1. Wear protective glasses, protective clothing and masks, gloves, and avoid contact with the skin during the experiment.
2. The waste generated after the experiment needs to be stored separately, and handed over to a professional biological waste gas treatment company to avoid environmental pollution.

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產品說明	酒石酸噻吩嘧啶(Pyrantel tartrate,33401-94-4)是一種殺線蟲噻吩
Introduction	Pyrantel tartrate(酒石酸噻吩嘧啶,33401-94-4) is an antinematodal thiophene
Application1
Application2
Application3

警示圖
危險性	warning
危險性警示	Not available
安全聲明	H303吞入可能有害+H313皮膚接觸可能有害+H2413吸入可能對身體有害
安全防護	P264處理后徹底清洗+P280戴防護手套/穿防護服/戴防護眼罩/戴防護面具+P305如果進入眼睛+P351用水小心沖洗幾分鐘+P338取出隱形眼鏡（如果有）并且易于操作,繼續沖洗+P337如果眼睛刺激持續+P2393獲得醫療建議/護理
備注	實驗過程中防止吸入、食入，做好安全防護

Parasite field study in central Kentucky on thoroughbred foals (born in 2004) treated with pyrantel tartrate daily and other parasiticides periodically Parasitology Research 2006/PMID: 17013652

Serum Strongylus vulgaris-specific antibody responses to anthelmintic treatment in naturally infected horses Parasitology Research 2014/PMID: 25358238

A light and electron microscopic study on the synergistic effect of pyrantel and the febantel metabolite febendazole on adult Toxocara canis in vitro Parasitology Research 2003/PMID: 12684883

Diagnosis and control of anthelmintic-resistant Parascaris equorum Parasites & Vectors 2009/PMID: 19778469

Transient effects of levamisole on Brugia malayi microfilariae Invertebrate Neuroscience 2015/PMID: 26187649

Activity of selected antioxidative enzymes in rats exposed to dimethoate and pyrantel tartrate

Abstract

This study presents the results of research concerning the effect of single and combined application of pyrantel tartrate and dimethoate on selected antioxidative enzymes: catalase (CAT), superoxide dismutase (SOD) and glutathione peroxidase (GPx), in rat erythrocytes. Pyrantel tartrate was applied twice, at a dose of 85 mg/kg bw at a two week interval, i.e. on day 14 and 28 of the experiment, orally, in a water solution with a stomach tube. Dimethoate was administered with drinking water for 28 days at a dose of 25 mg/kg bw/day. It was found that pyrantel tartrate caused only small changes in the activity of the antioxidative enzymes under analysis. Subchronic exposure of rats to dimethoate caused a significant increase in the activity of CAT, SOD and GPx in erythrocytes, indicating the existence of strong oxidative stress. In combined intoxication, no significant effects of administering pyrantel tartrate on the activity of CAT, SOD and GPx was found in animals poisoned with dimethoate. The profile of changes was similar to that observed in rats exposed only to the organophosphorus insecticide. This may indicate a lack of interaction between the compounds used in the experiment.

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