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Linoleoyl-coenzyme A

NMR下載 COA and HPLC MSDS下載
names：
Coenzyme A, S-9,12-octadecadienoate-
CAS號：
40757-80-0
MDL Number：
MF(分子式)： C39H67N7O18P3S MW(分子量)： 1046.97
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文別名	Linoleoyl-coenzyme A
英文別名	Linoleoyl-coenzyme A; Coenzyme A, linoleoyl-;
CAS號	40757-80-0
Inchi	InChI=1S/C21H36N7O16P3S.C18H32O2/c1-21(2,16(31)19(32)24-4-3-12(29)23-5-6-48)8-41-47(38,39)44-46(36,37)40-7-11-15(43-45(33,34)35)14(30)20(42-11)28-10-27-13-17(22)25-9-26-18(13)28;1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h9-11,14-16,20,30-31,48H,3-8H2,1-2H3,(H,23,29)(H,24,32)(H,36,37)(H,38,39)(H2,22,25,26)(H2,33,34,35);6-7,9-10H,2-5,8,11-17H2,1H3,(H,19,20)/p-1/b;7-6+,10-9+/t11-,14-,15-,16+,20-;/m1./s1
InchiKey	GISNRZPAZNWKHE-XFLCQTJPSA-M
分子式 Formula	C39H67N7O18P3S
分子量 Molecular Weight	1046.97
溶解度Solubility
性狀	Solid powder
儲藏條件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

產品說明	Linoleoyl-coenzyme A(CAS:40757-80-0):僅限應用于工業或者科學研究過程中非醫療目的，不應用于人類或動物的臨床診斷以及治過程療，該產品非藥用，非食用。
Introduction	Linoleoyl-coenzyme A is a substrate used to investigate the specificity and kinetics of acyl-CoA lysophosphatidylcholine acyltransferase (LPCAT) and mitochondrial linoleoyl-coenzyme monolysocardiolipin acyltransferase-1 (MLCL AT-1).
Application1
Application2
Application3

警示圖
危險性	Warning
危險性警示
安全聲明
安全防護
備注

[1]Taylor WA, Hatch GM. Identification of the human mitochondrial linoleoyl-coenzyme A monolysocardiolipin acyltransferase (MLCL AT-1). J Biol Chem. 2009 Oct 30;284(44):30360-7[1]doi: 10.1074/jbc.M109.048322. Epub 2009 Sep 8. PubMed PMID: 19737925; PubMed Central PMCID: PMC2781591.

[2]Taylor WA, Hatch GM. Purification and characterization of monolysocardiolipin acyltransferase from pig liver mitochondria. J Biol Chem. 2003 Apr 11;278(15):12716-21. Epub 2003 Feb 4. PubMed PMID: 12569106.

[3] Deutsch J, Grange E, Rapoport SI, Purdon AD. Isolation and quantitation of long-chain acyl-coenzyme A esters in brain tissue by solid-phase extraction. Anal Biochem. 1994 Aug 1;220(2):321-3. PubMed PMID: 7978274.

[4] Young AJ, Barker KL. Effect of estradiol and progesterone on long chain fatty acyl-coenzyme A levels in the rat uterus. Biochim Biophys Acta. 1991 Apr 17;1092(2):211-7. PubMed PMID: 2018788.

[5] Kawashima Y, Kozuka H. Regulation of palmitoyl-CoA chain elongation and linoleoyl-CoA chain elongation in rat liver microsomes and the differential effects of peroxisome proliferators, insulin and thyroid hormone. Biochim Biophys Acta. 1985 Mar 27;834(1):118-23. PubMed PMID: 3884049.

6: Okayasu T. [Purification and characterization of Linoleoyl-CoA desaturase from rat liver microsomes (author's transl)]. Hokkaido Igaku Zasshi. 1981 Jan;56(1):43-54. Japanese. PubMed PMID: 7262818.7: Taylor WA, Mejia EM, Mitchell RW, Choy PC, Sparagna GC, Hatch GM. Human trifunctional protein alpha links cardiolipin remodeling to beta-oxidation. PLoS One. 2012;7(11):e48628. doi: 10.1371/journal.pone.0048628. Epub 2012 Nov 9. PubMed PMID: 23152787; PubMed Central PMCID: PMC3494688.8: Ayyash M, Algahmi A, Gillespie J, Oelkers P. Characterization of a lysophospholipid acyltransferase involved in membrane remodeling in Candida albicans. Biochim Biophys Acta. 2014 Apr 4;1841(4):505-13. doi: 10.1016/j.bbalip.2013.12.015. Epub 2014 Jan 7. PubMed PMID: 24406902; PubMed Central PMCID: PMC4169218.9: Prasad MR, Nagi MN, Ghesquier D, Cook L, Cinti DL. Evidence for multiple condensing enzymes in rat hepatic microsomes catalyzing the condensation of saturated, monounsaturated, and polyunsaturated acyl coenzyme A. J Biol Chem. 1986 Jun 25;261(18):8213-7. PubMed PMID: 3722151.10: Retamal MA, Evangelista-Martínez F, León-Paravic CG, Altenberg GA, Reuss L. Biphasic effect of linoleic acid on connexin 46 hemichannels. Pflugers Arch. 2011 Jun;461(6):635-43. doi: 10.1007/s00424-011-0936-3. Epub 2011 Mar 1. PubMed PMID: 21360038; PubMed Central PMCID: PMC3108795.1

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